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1.
Appl Opt ; 63(7): 1839-1846, 2024 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-38437288

RESUMO

The spectral information contained in the reflective imaging bands can be exploited for specific tasks. Whether targeting or mapping, the visible (VIS), near-infrared (NIR), shortwave infrared (SWIR), extended shortwave infrared (eSWIR) bands perform very differently for every application. For any imaging project, high contrast is very important for good imagery. High contrast leads to more recognizable features within a scene and easier identifiable objects. For mapping, good background scene contrast gives prominent features more detail and their locations can be easily identified. For targeting, low background scene contrast reduces clutter, making it easier to detect objects of interest. The VIS, NIR, SWIR, and eSWIR bands are popular reflective bands to design daytime imaging systems for either task. Deciding on which band will have the best contrast for a specific task is one of the first things to study when designing an imaging system. By measuring urban and rural scenes in terms of equivalent reflectivity (ER), a direct comparison of these four bands can show the utility they provide. The systems used to measure scene contrast are designed to have the same spatial resolution and field of view (FOV). With these instantaneous FOV (IFOV) matched systems, the variance and 1D power spectral densities (PSDs) provide a quantitative comparison for the contrast among the four bands. The ER differences and resulting contrast measured among these four bands show that the eSWIR has the highest contrast in both urban and rural scenes.

2.
MicroPubl Biol ; 20222022.
Artigo em Inglês | MEDLINE | ID: mdl-36506349

RESUMO

Understanding the roles of evening complex (EC) genes in the circadian clock of plants can inform how diurnal transcriptional loops in the clock gene network function to regulate key physiological and developmental events, including flowering transition. Gene regulatory interactions among soybean's circadian clock and flowering genes were inferred using time-series RNA-seq data and the network inference algorithmic package CausNet. In this study, we seek to clarify the inferred regulatory interactions of the EC gene GmELF3-1. A gene expression analysis using soybean protoplasts as a transient model indicated regulatory roles of GmELF3-1 in expression of selected flowering genes.

3.
J Pharm Pract ; 27(5): 470-3, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24395009

RESUMO

INTRODUCTION: The concurrent use of cigarettes while on warfarin therapy is a common occurrence. Smoking cessation among patients on chronic warfarin therapy is suspected to reduce drug clearance that may require dose adjustments. This type of interaction is particularly important when dealing with narrow therapeutic medications, as is the case with warfarin. Our case describes a series of supratherapeutic international normalized ratios (INRs) due to smoking cessation while on concomitant warfarin therapy. Patient Case: A 51-year-old male presented to the anticoagulation clinic for management of his warfarin therapy for an acute deep vein thrombosis. After 2 months of stable, therapeutic INR levels, the patient abruptly decreased his smoking from 1 pack/day to one-half pack/day and then subsequently stopped smoking completely. The patient's smoking cessation resulted in a major modification of his required weekly warfarin dose to maintain a therapeutic INR (a 39% dose reduction). CONCLUSION: This case exemplifies how certain lifestyle factors, such as smoking, can alter the pharmacokinetics of patients on chronic warfarin therapy. This is the first case to demonstrate a greater than 30% reduction in the weekly warfarin dose following smoking cessation.


Assuntos
Anticoagulantes/administração & dosagem , Abandono do Hábito de Fumar , Fumar/metabolismo , Varfarina/administração & dosagem , Anticoagulantes/uso terapêutico , Relação Dose-Resposta a Droga , Interações Medicamentosas , Humanos , Coeficiente Internacional Normatizado , Masculino , Pessoa de Meia-Idade , Trombose Venosa/tratamento farmacológico , Varfarina/uso terapêutico
4.
J Pharm Pract ; 26(3): 257-60, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22869910

RESUMO

INTRODUCTION: Management of severe symptomatic anemia in critically ill Jehovah's Witness patients remains a challenge. The paucity of therapeutic alternatives to human red blood cells has prompted the use of blood substitutes. CASE REPORT: A 19-year-old female Jehovah's Witness patient presented to the emergency department following several episodes of syncope. She was found to have a positive Coombs test and was diagnosed with warm-bodied autoimmune hemolytic anemia. Upon admission, her hemoglobin was 8.4 g/dL, then dropped to a nadir of 2.8 g/dL 4 days later. She received traditional management with corticosteroids, intravenous immune globulin, rituximab, and partial splenic artery embolization. Despite these therapies, hemoglobin levels failed to respond, and she experienced signs of marked ischemia. A decision was made to give 2 units of Hemopure, a bovine hemoglobin-based oxygen carrier, and the hemoglobin levels increased to 8.7 g/dL 10 days later. The patient's overall clinical condition improved leading to subsequent hospital discharge. CONCLUSION: This case exemplifies the ingenuity that health care practitioners must use in critical situations involving the medical management of anemic Jehovah's Witness patients who refuse blood products. Hemopure was used as "bridging treatment" to help save a patient from the devastating effects of ischemia resulting from severe anemia.


Assuntos
Anemia Hemolítica Autoimune/terapia , Substitutos Sanguíneos/administração & dosagem , Hemoglobinas/administração & dosagem , Testemunhas de Jeová , Doença Aguda , Animais , Bovinos , Teste de Coombs , Feminino , Hemoglobinas/metabolismo , Humanos , Síncope/etiologia , Resultado do Tratamento , Recusa do Paciente ao Tratamento , Adulto Jovem
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